1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt), >99.99%，1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)
产品编号XIYU-BP378752
Cas号108392-02-5
纯度/浓度
储存温度-20°C
规格
￥0.00 ~ 4,947.00元
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- 中文名称：1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt), >99.99%
- 英文名称：1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)
- CAS NO：108392-02-5
- 分子式：C39H72O8PNa
- 分子量：722.95
基本信息
| 用途: | Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation. |
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| 储存条件: | -20°C |
| 物化性质: | |
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