MSA-2, 98%，MSA-2
产品编号XIYU-BP146942
Cas号129425-81-6
纯度/浓度
储存温度-20°C，密闭，干燥
规格
￥0.00 ~ 8,684.00元
增值税发票√顺丰快递√订货电话：18601927057
- 中文名称：MSA-2, 98%
- 英文名称：MSA-2
- CAS NO：129425-81-6
- 分子式：C14H14O5S
- 分子量：294.32
基本信息
| 用途: | MSA-2 is an orally available human STING agonist.MSA-2 is bound to STING as a noncovalent dimer. Extensive experimental analysis indicates that MSA-2 predimerization is required for binding. Acidic tumor microenvironments favor permeable, uncharged MSA-2. Intracellular MSA-2 is "trapped" and accumulation drives MSA-2 dimerization, preferentially activating STING intratumorally. Orally dosed MSA-2 is well tolerated in mice, exhibiting STING-dependent antitumor activity, as monotherapy and combined with antibodies against PD1 (anti-PD1). |
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| 储存条件: | -20°C，密闭，干燥 |
| 物化性质: | |
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